Publications

  1. Cherkaoui S, Turn CS, Yuan Y, Lu W, Yang L, McBride MJ, Eigenmann C, Allen GE, Panasenko OO, Zhang L, Vu A, Liu K, Li Y, Gandhi OH, Surrey LF, Kienast SD, Leidel SA, Wierer M, White E, Rabinowitz JD, Hogarty MD, Morscher RJ. Reprogramming neuroblastoma by diet-enhanced polyamine depletion. Nature. 2025

  2. Roichman A, Zuo Q, Hwang S, Lu W, Cordova RA, MacArthur MR, Boyer JA, Mitchell SJ, Powers J, Koval SA, Hunter CJ, Rijmers J, Ryseck RP, AbuSalim JE, Chatterjee S, Lee WD, Xu X, Xing X, Chen Z, Zeng X, Marwaha S, McBride MJ, Guo JY, Kang Y, Donia MS, Rabinowitz JD. Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors. Cell. 2025

  3. Hagen JT, Montgomery MM, Aruleba RT, Chrest BR, Krassovskaia P, Green TD, Pacheco EA, Kassai M, Zeczycki TN, Schmidt CA, Bhowmick D, Tan SF, Feith DJ, Chalfant CE, Loughran TP Jr, Liles D, Minden MD, Schimmer AD, Shakil MS, McBride MJ, Cabot MC, McClung JM, Fisher-Wellman KH. Acute myeloid leukemia mitochondria hydrolyze ATP to support oxidative metabolism and resist chemotherapy. Sci Adv. 2025

  4. Geraghty S, Boyer JA, Fazel-Zarandi M, Arzouni N, Ryseck RP, McBride MJ, Parsons LR, Rabinowitz JD, Singh M. Integrative Computational Framework, Dyscovr, Links Mutated Driver Genes to Expression Dysregulation Across 19 Cancer Types. bioRxiv. 2024

  5. Long D Jr, Chan M, Han M, Kamdar Z, Ma RK, Tsai PY, Francisco AB, Barrow J, Shackelford DB, Yarchoan M, McBride MJ, Orre LM, Vacanti NM, Gujral TS, Sethupathy P. Proteo-metabolomics and patient tumor slice experiments point to amino acid centrality for rewired mitochondria in fibrolamellar carcinoma. Cell Rep Med. 2024.

  6. Lu W, McBride MJ, Lee WD, Xing X, Xu X, Li X, Oschmann AM, Shen Y, Bartman C, Rabinowitz JD. Selected Ion Monitoring for Orbitrap-Based Metabolomics. Metabolites, 2024.

  7. Cherkaoui, S., Yang, L., McBride, M.J., Turn, C.S, Lu, W., Eigenmann, C., Allen, G.E., Panasenko, O.O., Zhang, L., Vu, A., Liu, K., Li, Y., Gandhi, O.H., Surrey, L., Wierer, M., White, E., Rabinowitz J.D., Hogarty, M.D., Morscher, R.J. Reprogramming neuroblastoma by diet-enhanced polyamine depletion. bioRxiv, 2024.

  8. McBride, M.J., Hunter, C.J., Zhang, Z., TeSlaa, T., Xu, X., Ducker, G.S., Rabinowitz, J.D. “Glycine homeostasis requires reverse SHMT flux.” Cell Metabolism, 36:103-115, 2024.

  9. Jones, B.M., Rubin, B.E.R., Dudchenko, O, Kingwell, C.J., Traniello, I.M., Wang, Z.Y., Kapheim, K.M., Wyman, E.S., St. Hilaire, B.G., Liu, W., Parsons, L.R., Jackson, S.R., Goodwin, K., Davidson, S.M., McBride, M.J., Webb, A.E., Omufwoko, K.S., Dorp, N.V., Otárola, M.F., Pham, M., Omer, A.D., Weisz, D., Schraiber, J., Villanea, F., Wcislo, W.T., Paxton, R.J., Hunt, B.G., Aiden, E.L., Kocher, S.D. “Convergent and complementary selection shaped gains and losses of eusociality in sweat bees.” Nature Ecology and Evolution, 2023.

  10. Yang, L., TeSlaa, T., Ng, S., Nofal, M., Wang, L., Lan, T., Zeng, X., Cowan, A., McBride, M.J., Lu, W., Davidson, S., Liang, G., Gyu Oh, T., Downes, M., Evans, R., Von Hoff, D., Guo, J.Y., Han, H., Rabinowitz, J.D. “Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth.” Med, 3:119-136, 2022.

  11. Ghergurovich, J.M., Lang, J.D., Levin, M.K., Briones, N., Facista, S.J., Mueller, C., Cowan A.J., McBride, M.J., Rodriguez, E.S.R., Killian, A., Dao, T., Lamont, J., Barron, A., Su, X., Hendricks, W.P.D., Espina, V., Von Hoff, D.D., O’Shaughnessy, J., Rabinowitz, J.D. “Local production of lactate, ribose phosphate, and amino acids by human triple-negative breast cancer.” Med, 2:736-754, 2021.

  12. Livnat, J.A., Neftel, C., Shore, M.E., McBride, M.J., Haas, B., Izar, B., Volorio, A., Boulay, G., Cironi, L., Richman, A.R., Broye, L.C., Gurski, J.M., Luo, C.C., Mylvaganam, R., Nguyen, L., Mei, S., Melms, J.C., Georgescu, C., Cohen O., Buendia, J., Cuoco, M.S., Labes, D., Zollinger, D.R., Beechem, J.M., Nielsen, G.P., Chebib, I., Cote, G., Choy, E., Letovanec, I., Cheriz, S., Wagle, N., Sorger, P.K., Haynes, A.B., Mullen, J.T., Stamenkovic, I., Rivera, M.N., Kadoch, C., Rozenblatt-Rosen, O., Suva, M.L., Riggi, N., Revev, A. “Opposing immune and genetic forces shape oncogenic programs in synovial sarcoma.” Nature Medicine, 27:289-300, 2021.

  13. McBride, M. J., Mashtalir, N., Winter, E. B., D’Avino, A. R., Zullow, H. J., Umbreit, N. T., Seo, H. S., Bridgers, J. B., Jaffe, J. D., Dhe-Paganon, S., Strahl, B. D., Kadoch, C. “Interplay between the nucleosome acidic patch and ubiquitylated histone H2A underlies cancer-specific recruitment of the mSWI/SNF chromatin remodeling complex.” Nature Structural & Molecular Biology, 27:836-845, 2020.  

  14. Baranov, E., McBride, M.J. (co-first author), Bellizzi, A.M., Ligon, A.H., Fletcher, C.D.M., Kadoch, C., Hornick, J.L. “A Novel SS18-SSX Fusion-specific Antibody for the Diagnosis of Synovial Sarcoma.” The American Journal of Surgical Pathology, 44:922-933, 2020.  

  15. Michel, B. C., D’Avino, A. R., Cassel, S. H., Mestalir, N., McKenzie, Z. M., McBride, M. J., Valencia, A. M., Zhou, Q., Bocker, M., Soares, L. M., Pan, J., Remillard, D. I., Lareau, C. A., Zullow, H. J., Fortoul, N., Gray, N. S., Bradner, J. E., Chan, H. M., Kadoch, C. “A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation.” Nature Cell Biology, 20:1410-1420, 2018.

  16. Sandoval, G. J., Pulice, J. L., Pakula, H., Schenone, M., Takeda, D. Y., Pop, M., Boulay, G., Williamson, K. E., McBride, M. J., Pan, J., St. Pierre, R., Hartman, E., Garraway, L. A., Carr, S. A., Rivera, M. N., Li, Z., Ronco, L., Hahn, W. C., Kadoch, C. “Binding of TMPRSS2-ERG to BAF chromatin remodeling complexes mediates prostate oncogenesis.” Molecular Cell, 71:554-566, 2018.

  17. McBride, M. J., Pulice, J. L., Beird, H. C., Ingram, D. R., D’Avino, A. R., Shern, J. F., Charville, G. W., Hornick, J. L., Nakayama, R. T., Garcia-Rivera, E. M., Araujo, D., Wang, W., Tsai, J., Yeagley, M., Wagner, A. J., Futreal, P. A., Khan, J., Lazar, A. J., & Kadoch, C. “The SS18-SSX fusion oncoprotein hijacks BAF complex targeting and function to drive synovial sarcoma.” Cancer Cell. 33:1128-1141, 2018. *Selected for journal cover

  18. McBride, M. J. & Kadoch, C. Disruption of mammalian SWI/SNF and polycomb complexes in human sarcomas: mechanisms and therapeutic opportunities. The Journal of Pathology, 244:638-649, 2018.

  19. Nakayama, R. T., Pulice, J. L., Valencia, A. M., McBride, M. J., McKenzie, Z. M., Gillespie, M. A., Ku, W. L., Teng, M., Cui, K., Williams, R. T., Cassel, S. H., Qing, H., Widmer, C. J., Demetri, G. D., Irizarry, R. A., Zhao, K., Ranish, J. A. & Kadoch, C. “SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters.” Nature Genetics, 49:1613-1623, 2017.

  20. Boulay, G., Sandoval, G. J., Riggi, N., Iyer, S., Buisson, R., Naigles, B., Awad, M. E., Rengarajan, S., Volorio, A., McBride, M. J., Broye, L. C., Zou, L., Stamenkovic, I., Kadoch, C. & Rivera, M. N. “Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain.” Cell, 171:163-178, 2017.

  21. Bradley, J. C., Abraham, M. H., Acree, W. E., Jr., Lang, A. S., Beck, S. N., Bulger, D. A., Clark, E. A., Condron, L. N., Costa, S. T., Curtin, E. M., Kurtu, S. B., Mangir, M. I. & McBride, M. J. “Determination of Abraham model solute descriptors for the monomeric and dimeric forms of trans-cinnamic acid using measured solubilities from the Open Notebook Science Challenge.” Chemistry Central Journal, 9:1-6, 2015.